Personnel due to receive the AstraZeneca COVID-19 vaccine at the Radisson Blu have had their appointment deferred.

All vaccination centres that were due to administer the AstraZeneca vaccine on Tuesday have been advised to postpone in light of updated guidance received from the National Immunisation Advisory Committee, and the Department of Health on Monday evening.

Any individual that was due to attend AstraZeneca clinic is therefore advised not to do so. Approximately 600 people were due to travel to the Radisson to get their vaccine on Tuesday, The Clare Echo understands.

A spokesperson for UL Hospitals Group which operate the Radisson Blu vaccination centre stated,
“We will be in contact with patients in due course to rearrange their appointment. We apologise for any inconvenience”.

On 7 April 2021, the European Medicine Agency (EMA) announced that they had concluded an investigation into a number of very rare, unusual blood clots occurring with low platelets in people following vaccination with Vaxzevria (formerly COVID-19 Vaccine AstraZeneca). The EMA’s safety committee (PRAC) concluded that unusual blood clots with low blood platelets should be listed as very rare side effects of Vaxzevria/AstraZeneca but that the benefits of this vaccine continue to outweigh the risks.

Revised recommendations were issued by the National Immunisation Advisory Committee (NIAC) on Monday.

In line with these recommendations, all of those aged 60 years and older can get any authorised COVID-19 vaccine, including Vaxzevria/AstraZeneca;

Vaxzevria/AstraZeneca is not recommended for those aged under 60 years including those with medical conditions with very high or high risk of severe COVID-19 disease;

For people who have already received Vaxzevria/AstraZeneca:

• Those aged 60 years and older should continue to receive their second dose 12 weeks later as scheduled,
• Those aged under 60 years with an underlying condition (those identified in cohort 4 and cohort 7) should continue to receive their second dose 12 weeks later as scheduled,
• Those aged under 60 years with no underlying condition (therefore not identified in cohort 4 and cohort 7) should have the scheduled interval between their first and second doses extended to 16 weeks to allow for further assessment of the benefits and risks as more evidence becomes available,
• Those who have developed unusual blood clots with low platelets after the first dose of Vaxzevria/AstraZeneca should not be given a second dose.

As of 7 April, the Health Products Regulatory Authority (HPRA) has been notified of approximately 2,800 reports of suspected side effects associated with Vaxzevria/AstraZeneca, in the context of 204,270 doses administered. The HPRA confirms it has received notice of a case of special interest and is continuing to follow up on this to see if it fits the profile of the very rare blood clots which were the subject of the EMA review.

An additional small number of cases describing low platelet counts have been received and follow up is ongoing to rule out the presence of blood clots.

Acting Chief Medical Officer, Dr Ronan Glynn outlined, “We will continue to monitor the roll-out of Vaxzevria/AstraZeneca in Ireland and internationally in collaboration with the HPRA and the NIAC. The Department of Health, the HSE and the High-Level Taskforce will now work together to ensure that these updated recommendations are incorporated into the ongoing implementation of the vaccination programme”.